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Randomised controlled trial of a theory-based behavioural intervention to reduce formula milk intake

Lakshman R, Sharp SJ, Whittle F, Schiff A, Hardeman W, Irvine L, Wilson E, Griffin SJ, Ong KK. Arch Dis Child. 2018 May 14. pii: archdischild-2018-314784. doi: 10.1136/archdischild-2018-314784. [Epub ahead of print] Abstract OBJECTIVE: To assess the efficacy of a theory-based behavioural intervention to prevent rapid weight gain in formula milk-fed infants. DESIGN: In this single (assessor) […]

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Digital technology to facilitate Proactive Assessment of Obesity Risk during Infancy (ProAsk): a feasibility study.

Redsell SA, Rose J, Weng S, Ablewhite J, Swift JA, Siriwardena AN, Nathan D, Wharrad HJ, Atkinson P, Watson V, McMaster F, Lakshman R, Glazebrook C. BMJ Open. 2017 Sep 6;7(9):e017694. doi: 10.1136/bmjopen-2017-017694 Abstract OBJECTIVE: To assess the feasibility and acceptability of using digital technology for Proactive Assessment of Obesity Risk during Infancy (ProAsk) with the […]

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Determinants of Change in Physical Activity in Children 0-6 years of Age: A Systematic Review of Quantitative Literature.

Hesketh KR, O’Malley C, Paes VM, Moore H, Summerbell C, Ong KK, Lakshman R, van Sluijs EM Sports Med. 2016 Dec 17. [Epub ahead of print] Abstract BACKGROUND: Understanding the determinants of children’s health behaviours is important to develop successful behaviour-change interventions. OBJECTIVE: We aimed to synthesise the evidence around determinants (‘preceding predictors’) of change […]

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Premenopausal abnormal uterine bleeding and risk of endometrial cancer

M Pennant, R Mehta, P Moody, G Hackett, A Prentice, SJ Sharp, R Lakshman BJOG. 2016 Oct 20. doi: 10.1111/1471-0528.14385. [Epub ahead of print] Abstract BACKGROUND: Endometrial biopsies are undertaken in premenopausal women with abnormal uterine bleeding but the risk of endometrial cancer or atypical hyperplasia is unclear. OBJECTIVES: To conduct a systematic literature review […]

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Effectiveness of a behavioural intervention to prevent excessive weight gain during infancy (The Baby Milk Trial): study protocol for a randomised controlled trial

Rajalakshmi Lakshman, Fiona Whittle, Wendy Hardeman, Marc Suhrcke, Ed Wilson, Simon Griffin and Ken K Ong Trials 2015 16:442 DOI: 10.1186/s13063-015-0941-5 Abstract Background. Infancy is a period of rapid growth and habit formation and hence could be a critical period for obesity prevention. Excess weight gain during infancy is associated with later obesity and formula-fed […]

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Factors influencing obesogenic dietary intake in young children (0-6 years): systematic review of qualitative evidence.

Paes VM, Ong K, Lakshman R BMJ Open. 2015 Sep 16;5(9):e007396. doi: 10.1136/bmjopen-2014-007396. Abstract Background Obesogenic dietary intake is prevalent in young children and is associated with obesity and other adverse health outcomes in childhood and later in life. Objective To describe the barriers to and facilitators of obesogenic dietary intake in early childhood, in […]

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Determinants of sugar-sweetened beverage consumption in young children: a systematic review.

Veena Mazarello Paes, Kathryn Hesketh, Claire O’Malley,  Helen Moore, Carolyn Summerbell, Simon Griffin, Esther MF van Sluijs, Ken K Ong, Rajalakshmi Lakshman Obes Rev. 2015 Aug 7. doi: 10.1111/obr.12310. [Epub ahead of print] Abstract Sugar-sweetened beverage (SSB) consumption is associated with adverse health outcomes. Improved understanding of the determinants will inform effective interventions to reduce […]

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Using the Medical Research Council Framework for the Development and Evaluation of Complex Interventions in a Theory-Based Infant Feeding Intervention to Prevent Childhood Obesity: The Baby Milk Intervention and Trial

Rajalakshmi Lakshman, Simon Griffin, Wendy Hardeman, Annie Schiff, Ann Louise Kinmonth, and Ken K. Ong Journal of Obesity Volume 2014 (2014), Article ID 646504, 10 pages Abstract Introduction. We describe our experience of using the Medical Research Council framework on complex interventions to guide the development and evaluation of an intervention to prevent obesity by […]

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Protocol for systematic reviews of determinants/correlates of obesity-related dietary and physical activity behaviors in young children (preschool 0 to 6 years): evidence mapping and syntheses.

Lakshman R, Mazarello Paes V, Hesketh K, O’Malley C, Moore H, Ong K, Griffin S, van Sluijs E, Summerbell C. Syst Rev. 2013 May 10;2:28. doi: 10.1186/2046-4053-2-28 Abstract Background. The aim of these reviews is to inform the design and content of interventions to reduce obesity in young children. The behaviors that are associated with […]

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Higher maternal education is associated with favourable growth of young children in different countries

Lakshman R, Zhang J, Zhang J, Koch FS, Marcus C, Ludvigsson J, Ong KK, Sobko T J Epidemiol Community Health. 2013. doi:10.1136/jech-2012-202021 Abstract Background. Childhood growth affects long-term health and could contribute to health inequalities that persist throughout life. Methods. We compared growth data of 4-year-old to 6-year-old children born 1997–2002 in UK (n=15 168), Sweden […]

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